Urine Biomarker Calibration for Ovarian Cancer Diagnosis
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چکیده
This paper proposes a correction method for urine biomarkers for better diagnosis of the ovarian cancer. The biomarkers were obtained from each urine sample of 163 patients (cancer: 42, benign: 121). The logistic regression of the combinations of 2 biomarkers calibrated by creatinine concentration was compared with that of the 3 biomarkers including creatinine. The average AUC over 100 repeated 5-fold cross validations was employed to evaluate the performance. The logistic regression of the calibrated biomarkers showed better performance than that without calibration for the top 10 combinations.
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تاریخ انتشار 2013